Substance P Causes Seizures in Neurocysticercosis

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Substance P Causes Seizures in Neurocysticercosis

Neurocysticercosis (NCC), a helminth infection of the brain, is a major cause of seizures. The mediators responsible for seizures in NCC are unknown, and their management remains controversial. Substance P (SP) is a neuropeptide produced by neurons, endothelial cells and immunocytes. The current studies examined the hypothesis that SP mediates seizures in NCC. We demonstrated by immunostaining ...

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ژورنال

عنوان ژورنال: PLoS Pathogens

سال: 2012

ISSN: 1553-7374

DOI: 10.1371/journal.ppat.1002489